Table 3. Changes of mean Cognitive Impairment Index (CII) values and of the mean FSS Score over 1 and 2 years of NTZ treatment.
| Parameter | Timepoint | Mean [SD] | p value |
| CII (n = 100) | Baseline | 13.52 [6.85] | <.0001* |
| Year 1 | 10.48 [7.12] | ||
| CII (n = 53) | Baseline | 12.94 [7.09] | <.0001† |
| Year 1 | 9.64 [6.89] | <.0001§ | |
| Year 2 | 8.26 [6.75] | .008θ | |
| FSS (n = 100) | Baseline | 4.01 [1.63] | .008* |
| Year 1 | 3.61 [1.56] | ||
| FSS (n = 53) | Baseline | 4.30 [1.58] | .004 † |
| Year 1 | 3.70 [1.41] | N.S.θ | |
| Year 2 | 3.49[1.75] | .001§ |
*
Wilcoxon signed-rank test;
†
Wilcoxon signed-rank test pair-wise comparison: Year 1 vs Baseline;
§
Wilcoxon signed-rank test pair-wise comparison: Year 2 vs Baseline;
θ
Wilcoxon signed-rank test pair-wise comparison: Year 1 vs Year 2.