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. 2012 Apr 25;7(4):e35973. doi: 10.1371/journal.pone.0035973

Figure 4. Analysis of active site residues.

Figure 4

Superposition of the HsDHCH (green) - NADP+ (yellow) - LY354899 (black) complex (PDB code: 1DIB) onto the remodeled PaFolD structure (grey). Residues that interact with either NADP+ or LY354899 molecules in HsDHCH and their counterparts in PaFolD structure are shown as sticks.