Table 6. Association of abnormal anal cytology and HPV genotypes among study participants.

Anal infection of 26 HPV types	Abnormal/Normal	Adjusted OR* (95% CI)	ASCUS/Normal	Adjusted OR* (95% CI)	(ASIL/ASC-H)/Normal	Adjusted OR* (95% CI)
High-Risk types infection
Negative for high-risk types	10/26	Ref.	6/26	Ref.	4/26	Ref.
Positive for high-risk types	26/29	2.02 (0.77–5.29)	13/29	1.63 (0.49–5.43)	13/29	2.48 (0.68–9.00)
p for difference		0.15		0.43		0.17
By multiplicity of HPV types
0	8/19	Ref.	5/19	Ref.	3/19	Ref.
1	12/25	1.22 (0.40–3.72)	6/25	0.83 (0.20–3.41)	6/25	1.71 (0.36–8.02)
2	9/7	3.81 (1.00–14.61)	5/7	4.08 (0.79–21.11)	4/7	4.71 (0.77–28.61)
≥3	7/4	4.71 (1.02–21.76)	3/4	2.71(0.41–17.82)	4/4	7.49 (1.07–52.21)
p for trend		0.04		0.20		0.04

Abbreviation: ASCUS = atypical squamous cells of undetermined significance; ASC-H = atypical squamous cells but cannot exclude HSIL; ASIL = anal squamous intraepithelial lesions, include low-grade squamous intraepithelial lesion (LSIL) and high-grade squamous intraepithelial lesion (HSIL); CI = confidence intervals; HPV = human papillomavirus; OR = odds ratio.

^*Adjusted for age, education, age at the first homosexual act, frequency of homosexual behaviors in the past 6 months and ever found sexual partners in gay venues.