Table 1. A comparison of egl-4 mutant phenotypes in C. elegans and P. pacificus.
egl-4 mutation | body length | fat storage | pharyngeal pumping | Forward movement | egg holding | odor sensing | odor adaptation |
Cel-egl-4(lf) | ↑26,31 | ↓25 | ↑# | ↑14 | ↑38 | ↓13 | ↓13 |
Ppa-egl-4(lf) | ↓16 | ↑* | ↑* | ↑* | no affect16 | ↓16 | ↓16 |
In C. elegans, the loss-of-function (lf) alleles n479 and ks62 have been used in multiple studies; In P. pacificus, only the loss-of-function null allele tu374 have been described. For fat storage measurements, Cel-egl-4(gf) and Ppa-egl-4(lf) alleles refer to Nile Red staining on fixed animals. *this study; #van Buskirk pers. comm; [13], [14], [16], [25], [26], [31], [38].