Figure 7. Novel alternations did not differ but mNPC treatment increased Trisomic performance above chance performance.

Overall, trisomic mice showed significantly fewer novel alternations compared to disomic mice (* p<0.05). Treatment with either saline or mNPC did not significantly change the number of novel alternations in either karyotype compared to their respective controls. However, trisomic mice treated with mNPC alternated significantly above chance alone (solid line), while untreated and saline treated trisomic mice did not. Mean ± SEM shown. * Significant main effect of karyotype. ∧ Novel alternations were significantly above chance.