Table 6. Most abundant superfamily domains in paraclusters.
| family | hs | xp | ru | mm | rn | dg | bv | op | gg | da |
| Family A G protein-coupled receptor-like | 379 (1) | 280 (2) | 322 (1) | 1300 (1) | 1229 (1) | 709 (1) | 377 (1) | 916 (1) | 49 (2) | 145 (2) |
| C2H2 and C2HC zinc fingers | 321 (2) | 301 (1) | 290 (2) | 259 (2) | 121 (3) | 53 (6) | 93 (3) | 275 (3) | 2 (126) | 76 (5) |
| KRAB domain (Kruppel-associated box) | 251 (3) | 234 (3) | 226 (4) | 235 (3) | 83 (4) | 89 (3) | 75 (4) | 250 (4) | 3 (101) | 0 |
| Immunoglobulin | 202 (4) | 190 (4) | 239 (3) | 212 (4) | 351 (2) | 275 (2) | 177 (2) | 283 (2) | 78 (1) | 168 (1) |
| Histone-fold | 62 (5) | 50 (9) | 62 (5) | 73 (8) | 39 (14) | 59 (4) | 30 (12) | 14 (30) | 26 (4) | 28 (16) |
| Intermediate filament protein, coiled coil region | 57 (6) | 56 (5) | 48 (6) | 57 (12) | 48 (8) | 55 (5) | 47 (6) | 35 (9) | 12 (17) | 22 (19) |
| Cadherin-like | 56 (7) | 53 (7) | 31 (11) | 46 (16) | 47 (10) | 46 (7) | 21 (19) | 37 (7) | 29 (3) | 47 (11) |
| Trypsin-like serine proteases | 56 (8) | 51 (8) | 42 (8) | 104 (5) | 83 (5) | 45 (8) | 44 (7) | 30 (14) | 11 (20) | 83 (3) |
| C-type lectin-like | 52 (9) | 53 (6) | 44 (7) | 86 (6) | 65 (6) | 35 (10) | 47 (5) | 31 (11) | 18 (6) | 57 (7) |
| Homeodomain-like | 39 (10) | 38 (10) | 35 (10) | 82 (7) | 55 (7) | 38 (9) | 35 (9) | 30 (13) | 23 (5) | 57 (8) |
| P-loop containing nucleoside triphosphate hydrolases | 25 (19) | 19 (27) | 24 (16) | 20 (33) | 15 (38) | 24 (15) | 39 (8) | 32 (10) | 10 (23) | 77 (4) |
| Periplasmic binding protein-like I | 0 | 0 | 0 | 18 (43) | 48 (9) | 0 | 0 | 71 (5) | 0 | 45 (12) |
The top 5 superfamilies having the most paracluster genes were selected from each vertebrate species tested and the number of genes along with the superfamily rank is provided for each species. hs = human, xp = chimp, ru = macaque, mm = mouse, rn = rat, dg = dog, bv = cow, op = opossum, gg = chicken, da = zerbrafish.