Figure 7. PAI-1 knockdown in human endothelial cells is associated with increased survival after irradiation.

Representative western blots and quantification of PAI-1 protein expression 8 hours (A) and 24 hours (B) after irradiation in the absence or presence of siPAI-1. Percentage of living cells 24 hours after irradiation in the absence or presence of siPAI-1 (C). Results are the mean +/− SEM of two independent experiments performed in triplicate. * p<0.05 versus unirradiated HUVECs. Representative images of HUVECs 24 hours after 20 Gy in the absence or presence of siPAI-1 (D).