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. 2012 Apr 26;7(4):e35926. doi: 10.1371/journal.pone.0035926

Figure 2. Expression of TLR4 in lung fibroblasts and its effect on lung fibroblast proliferation.

Figure 2

TLR4 mRNA (A, real-time PCR) and protein (B, Western blot) expression in lung fibroblasts at 72 hours after 1 µg/mL LPS challenge. Effect of siRNA-mediated knockdown of TLR4 (1×108 TU/mL for 48 hours) on lung fibroblast proliferation (C, BrdU assay). * p<0.05 vs. negative control group (Column 2); † p<0.05 vs. positive control group (Column 3). Columns represent mean values and error bars represent SD. Blots are representative of three independent experiments.