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. 2012 Apr 27;7(4):e36316. doi: 10.1371/journal.pone.0036316

Figure 4. c-Fos expression and Fluorescent staining of Nucleus Accumbens in sIL-2Rs treated mice.

Figure 4

Photomicrographs of brain sections showing Fos-like immunoreactive cells in the nucleus accumbens of mice receiving single injection of (A) saline, (B) 1 µg sIL-2Rα or (C) 2 µg sIL-2Rβ. Abbreviations: aca, anterior commissure; Sh, shell of nucleus accumbens; Co, core of nucleus accumbens. (D) Histogram show the number (mean ± S.E.M.) indicate Fos-positive cells counted within the indicated compartments of the nucleus accumbens after administration of saline or single injections of sIL-2Rα or sIL-2Rβ. Photomicrographs of deposits of sIL-2Rα or sIL-2Rβ in shell or core of nucleus accumbens after administration of (E and F) saline or single injections of (G and H) sIL-2Rα or (I and J) sIL-2Rβ. Photomicrographs showing merged c-Fos and Fluorescent staining in sIL-2Rα treated mice (K) and sIL-2Rβ treated mice (L). [Arrow head: - Fluorescent staining; Arrow: - c-fos staining].