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. 2012 Apr 27;7(4):e36316. doi: 10.1371/journal.pone.0036316

Table 1. Effect of various doses of sIL-1R1 on different open field behaviors.

Parameter Saline sIL-1R1 µg sIL-1R 2 µg sIL-1R 4 µg sIL-1R 8 µg f p
Locomotion (cm) 6624.08±3198.82 7762.83±3394.46 7518.11±3540.1 7393.47±1909.66 4499.7±2113.78 f (4, 34) = 1.83 0.15
Rearing Episodes (#) 40.3±21.9 44.43±18.4 37.43±12.4 37.7±18.24 36.2±26.62 f (4, 34) = 0.19 0.94
Turning 29.5±13.91 33±11.87 35±17.37 30.88±10.04 21.66±13.93 f (4, 34) =  0.91 0.47
Sniffing (sec) 461.5±135.41 389.6±77 415.75±91.14 455±107.53 N/A f (3,12) = 0.46 0.71
Head Bobbing 36.33±3.78 37±17.8 14.2±19 32±31.66 3±4.24 f(3,14) = 1.12 0.37
Vertical Stereotypy Moves 36.25±37.03 36±24.74 15.5±3.31 42.67±23.11 N/A f (3,12) = 0.82 0.5
Vertical Stereotypy Episodes 16.25±16.04 15.8±10.23 7±1.63 18.67±9.01 N/A f (3,12) = 0.87 0.48

Table shows effects of various doses of single injection of sIL-1R1 on various behaviors in open field testing. Effects was considered significance if p<0.05.