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Follicular loss is independent of AIRE expression intrinsic to the ovary. Aire-deficient (A and B) and wild-type (C) mice were engrafted with a donor wild-type ovary under the kidney capsule and euthanized after 10 days. Grafts and endogenous ovaries were harvested for histological analysis. A–C represent the grafted ovary; D and E represent the endogenous ovary of the Aire-deficient recipients. Original magnification ×100.
