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. 2012 Apr 27;7(4):e35669. doi: 10.1371/journal.pone.0035669

Table 1. pKa of selected VDE residues.

Residue pKa std
ASP86 5.0 0.1
ASP98 5.3 0.2
ASP117 5.3 0.3
HIS168 7.0 0.3
ASP206 5.2 0.1

pKa values of all ionizable residues are shown in Table S1. Here are reported the ones identified as putatively responsible of the pH dependent activation, having pKa between 5 and 7 in VDEpH7.