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. 2012 Apr 27;7(4):e35462. doi: 10.1371/journal.pone.0035462

Table 2. Correlations of secondary measures with MHFMS and age for SMA subjects.

MHFMS Age
Age 0.07 (p = 0.45)
BMI z-score 0.17 (p = 0.09) 0.12(p = 0.20)
FVC % predicted 0.70 (p<0.001) −0.14(p = 0.31)
10 meter walk −0.28 (p = 0.13) −0.36(p = 0.045)

Of the secondary outcome measures, only forced vital capacity (FVC) significantly correlated with the primary outcome measure – the Modified Hammersmith Motor Function Scale. While BMI is thought to have a strong effect on function in individuals affected by SMA, the correlation did not reach significance here. Not surprisingly, FVC and walking were negatively correlated with age.