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. 2012 Apr 27;7(4):e35979. doi: 10.1371/journal.pone.0035979

Figure 2. NOMID mice develop leukocytosis associated with high levels of inflammatory mediators.

Figure 2

Complete blood cell counts (A) and serum cytokine analysis (B) were carried out on samples harvested from P12–13 mice (n = 4–7). NOMID mice developed neutrophilia, lymphopenia, thrombocytosis and anemia and produced higher levels of several inflammatory mediators. G-CSF values were extrapolated beyond the standard range. IL-6 and TNF-α levels were near statistical significance between genotypes. Data are expressed as mean ± S.E.M. *P<0.05, **P<0.007. WBC, white blood cells; RBC, red blood cells.