Table 1. Pathogenic bacteria used in this study (set 2).
Species | Disease | Mode of transmission | Proteins |
Bacteria causing acute infections (set 2 a) | |||
Bacillus anthracis (Sterne) | Anthrax | Contact with infected animals | 5284 |
Bartonella bacilliformis (ATCC 35685) | Oroya fever | Sandfly bites | 1255 |
Burkholderia mallei (ATCC 23344) | Glanders | Contact with infected animals | 4797 |
Campylobacter jejuni (RM1221) | Campylobacteriosis | Food; contact with animals | 1836 |
Clostridium tetani (E88) | Tetanus | Breaks in skin | 2415 |
Corynebacterium diphtheriae (ATCC 700971) | Diphtheria | Respiratory/physical contact | 2264 |
Coxiella burnetii (RSA 493) | Q-fever | Inhalation around animal reservoirs | 1815 |
Francisella tularensis (FSC 198) | Tularemia | Many; not person-to-person | 1528 |
Legionella pneumophila (Corby) | Legionnaires’ | Inhalation; not person-to-person | 3202 |
Leptospira interrogans (Fiocruz L1-130) | Leptospirosis | Animal urine-infected water/food | 3654 |
Listeria monocytogenes (ATCC BAA-679) | Listeriosis | Contaminated food | 2844 |
Streptococcus pneumoniae (CGSP14) | Pneumonia | Person-to-person | 2193 |
Vibrio cholerae (ATCC 39315) | Cholera | Contaminated food/water | 3784 |
Yersinia pestis (Angola) | Plague | Many, including person-to-person | 3821 |
Bacteria causing chronic infections (set 2 b) | |||
Borrelia burgdorferi (ATCC 35210) | Lyme Disease | Tick bites | 1556 |
Brucella abortus (9–941) | Brucellosis | Contaminated food/water | 3077 |
Chlamydia trachomatis (ATCC VR902B) | Chlamydia | Person-to-person (sexual) | 884 |
Haemophilus ducreyi (ATCC 700724) | Chancroid | Person-to-person (sexual) | 1694 |
Mycobacterium tuberculosis (Oshkosh) | Tuberculosis | Person-to-person (through the air) | 4201 |
Treponema pallidum (SS14) | Syphilis | Person-to-person (sexual) | 1028 |
The species name, associated disease, mode of transmission, and proteome size are listed for each bacterium. The specific strain used is indicated in parentheses after each species name. Some bacteria cause varying symptoms or diseases; as such, a representative disease was chosen for each. These bacteria constitute set 2 as described in the text, and were divided into sets 2 a and 2 b, which represent bacteria causing acute infections and bacteria causing chronic infections, respectively. Modes of transmission were derived from the Centres for Disease Control website (http://emergency.cdc.gov).