Table 2. Frequencies of Copy Number Rearrangements and Association with end stage AMD.

			End stage AMD						Unadjusted Analysis
	Controls (n = 327)		Unilateral GA (n = 33)		Bilateral GA (n = 86)		nAMD(n = 268)		Bilateral GA		nAMD		ALL AMD
	n	%	n	%	n	%	n	%	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value
CFHR3-1 Deletion
2 Copies	220	67.3	27	82	80	93	229	85.45	0.36 (0.25–0.52)	1.5×10−6	0.36 (0.25–0.52)	8.3×10−9	0.31 (0.23–0.44)	2.38×10−12
1 Copy	88	26.9	6	18	6	7	37	13.8
0 Copies	19	5.8	0	0	0	0	2	0.75
CFHR1-4 Deletion
2 Copies	325	99.4	33	100	82	95.3	266	99.26	7.6 (1.38–41.8)	0.02	0.6 (0.05–6.8)	1	2.1 (0.40–10.91)	0.46
1 Copy	2	0.006	0	0	4	4.7	2	0.74
0 Copies	0	0	0	0	0	0	0	0