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Schematic representation of UDP-3-O-(R-3-hydroxymyristoyl)-GlcN enzymatic preparation. The LpxA catalyzed formation of UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc is coupled directly to LpxC to form UDP-3-O-(R-3-hydroxymyristoyl)-GlcN, while AasS catalyzes the acylation of holo-ACP to regenerate acyl-ACP.
