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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Biochim Biophys Acta. 2012 Feb 23;1822(6):862–874. doi: 10.1016/j.bbadis.2012.02.017

Figure 11.

Figure 11

Mitochondrial functional parameters in Drp1+/+ mice and Drp1+/− mice. (A) represents hydrogen peroxide in cerebral cortex and cerebellum tissues from Drp1+/− mice and Drp1+/+ mice. Significantly reduced hydrogen peroxide production was found in the cerebral cortex of Drp1+/− mice compared to Drp1+/+ mice (P<0.05). (B) represents cytochrome oxidase activity. Cytochrome oxidase activity was unchanged in the cerebral cortex and cerebellum tissues from Drp1+/− mice compared to Drp1+/+ mice. (C) represents lipid peroxidation in cerebral cortex and cerebellum tissues from Drp1+/− mice and Drp1+/+ mice. Significantly reduced lipid peroxidation levels were found in the cerebral cortex of Drp1+/− mice compared to Drp1+/+ mice (P<0.05). (D) represents synaptosomal mitochondrial ATP. Synaptosomal mitochondrial ATP was unchanged in the cerebral cortex and cerebellum tissues from Drp1+/− mice compared to Drp1+/+ mice.