Table 1.

NMR Spectroscopic Data (500 MHz for ¹H, 125 Hz for ¹³C, DMSO-d₆) for Totopotensamides A and B (1 and 2).

unit	No	1		2
		δC	δH (J in Hz)	δC	δH (J in Hz)
L-Gly	1	168.7, C	-	169.3, C	-
	2	43.7, CH2	4.07, m; 3.44, m	43.8, CH2	4.07, m; 3.42, m
	NH		8.07, m		8.05, m
L-Ile	1	172.0, C	-	171.6, C	-
JH2~H3 = 10.0 Hz in CD3OD	2	61.5, CH	3.77, m	61.9, CH	3.76, m
	3	35.6, CH	1.77, m	35.7, CH	1.75, m
	4	27.1, CH2	1.19, m; 1.05, m	27.1, CH2	1.23, m; 1.04, m
	5	11.5, CH3	0.78, t (6.3)	11.6, CH3	0.79, t (6.3)
	6	17.3, CH3	0.73, d (7.0)	17.2, CH3	0.74, d (7.0)
	NH		7.09, d (6.0)		7.09, d (6.0)
L-ClPhg	1	172.3, C	-	172.1, C	-
	2	57.7, CH	5.71, d (10.0)	57.7, CH	5.71 d (10.0)
	3	131.3, C	-	131.2, C	-
	4	111.8, C	-	112.0, C	-
	5	153.2, C	-	153.3, C	-
	6	114.5, C	-	114.6, C	-
	7	155.8, C	-	155.8, C	-
	8	107.9, CH	6.61, s	107.1, CH	6.61, s
	9	11.3, CH3	2.04, s	11.0, CH3	2.03, s
	NH		8.93, d (10.0)		8.90, d (10.1)
2R,3S-Dab	1	169.9, C	-	169.8, C	-
JH2~H3 = 3.5 Hz in CD3OD	2	56.4, CH	4.46, m	56.5, CH	4.45, m
	3	46.7, CH	4.16, m	47.1, CH	4.09, m
	4	16.5, CH3	1.06, d (6.7)	16.6, CH3	1.06, d (6.5)
	2-NH		8.02, d (8.2)		8.01, d (8.1)
	3-NH		6.24, d (9.7)		6.22, d (9.8)
L-Ala	1	172.9, C	-	173.0, C	-
	2	49.6, CH	4.35, m	49.7, CH	4.34, m
	3	19.6, CH3	1.19, d (7.0)	19.8, CH3	1.18, d (7.0)
	NH		8.05, d (8.0)		8.03, d (8.0)
D-allo-Thr	1	170.9, C	-	171.0, C	-
JH2~H3 = 12.0 Hz in CD3OD	2	59.8, CH	4.23, m	60.1, CH	4.21, m
	3	68.4, CH	3.80, m	68.6, CH	3.80, m
	4	21.1, CH3	1.07, d (6.7)	21.1, CH3	1.07, d (6.6)
	NH		8.24, d (8.1)		8.24, d (8.1)
Polyketide	1	167.5, C	-	167.6, C	-
	2	50.5, CH2	3.52, d (15.2); 3.42, d (15.2)	50.6, CH2	3.53, d (15.1); 3.41, d (15.1)
	3	210.4, C	-	210.4, C	-
	4	44.8, CH	2.74, m	44.8, CH	2.72, m
	5	40.4, CH2	1.73, m; 0.77, m	40.4, CH2	1.72, m; 0.77, m
	6	29.2, CH	1.38, m	29.1, CH	1.38, m
	7	42.6, CH2	1.12, m; 0.78, m	42.6, CH2	1.10, m; 0.76, m
	8	34.9, CH	1.50, m	34.9, CH	1.51, m
	9	73.9, CH	3.53, m	75.5, CH	3.44, m
	10	37.6, CH	1.75, m	37.7, CH	1.78, m
	11	88.4, CH	3.41, m	79.8, CH	3.19, m
	12	67.6, CH	3.61, m	68.3, CH	3.54, m
	13	20.3, CH3	1.04, d (6.0)	20.2, CH3	1.06, d (6.1)
	14	19.1, CH3	0.99, d (6.8)	19.1, CH3	0.99, d (6.8)
	15	22.6, CH3	0.81, d (6.4)	22.6, CH3	0.80, d (6.5)
	16	17.9, CH3	0.84, d (6.4)	17.9, CH3	0.82, d (6.4)
	17	17.3, CH3	0.73, d (6.9)	17.3, CH3	0.75, d (6.9)
Methyl-glucose	1′	104.8, CH	4.21, d (8.2)
	2′	75.3, CH	2.99, dd (9.0, 8.2)
	3′	77.9, CH	3.29, dd (9.0, 8.6)
	4′	80.8, CH	2.91, dd (9.0, 8.6)
	5′	76.9, CH	3.14, m
	6′	62.1, CH2	3.60, m, 3.46, m
	7′-OMe	61.3, CH3	3.41, s