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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Lab Invest. 2012 Jan 16;92(5):662–675. doi: 10.1038/labinvest.2011.198

Table 2.

QLα12LacZ+/Cre+ mice score higher for glomerular injury

Injury PODOCYTES GBM
FP EFF FP IRREG MICROVIL KNOBS DCs

Genotype C ++ C ++ C ++ C ++ C ++
Scores by Age (m) <12 0 0.33 0.75 1 0.5 0.33 0.25 0.67 0 0
12-18 1 0.6 1.3 1 1 1 1.67 1.4 0.33 1
18-24 0 1.5 0.33 1.8 0.66 1.25 1 2 0 1.2
Injury ENDOTHELIUM
SUBEND DEP SWELLING MES MATRIX MES CELLS

Genotype C ++ C ++ C ++ C ++

Scores by Age (m) <12 0 0 0 0.33 0.75 1 0.5 0.67
12-18 0 0.6 0 0.6 1 1.8 1 1.2
18-24 0 0.88 0 1 1.3 2.6 1.7 2.4

C=control Mice

++=QLα12LacZ+/Nphs2-Cre+ mice

FP=foot process

EFF=effacement

DC=double contours

MES=mesangial