Table 2.
Injury | PODOCYTES | GBM | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
FP EFF | FP IRREG | MICROVIL | KNOBS | DCs | |||||||
| |||||||||||
Genotype | C | ++ | C | ++ | C | ++ | C | ++ | C | ++ | |
Scores by Age (m) | <12 | 0 | 0.33 | 0.75 | 1 | 0.5 | 0.33 | 0.25 | 0.67 | 0 | 0 |
12-18 | 1 | 0.6 | 1.3 | 1 | 1 | 1 | 1.67 | 1.4 | 0.33 | 1 | |
18-24 | 0 | 1.5 | 0.33 | 1.8 | 0.66 | 1.25 | 1 | 2 | 0 | 1.2 |
Injury | ENDOTHELIUM | ||||||||
SUBEND DEP | SWELLING | MES MATRIX | MES CELLS | ||||||
| |||||||||
Genotype | C | ++ | C | ++ | C | ++ | C | ++ | |
| |||||||||
Scores by Age (m) | <12 | 0 | 0 | 0 | 0.33 | 0.75 | 1 | 0.5 | 0.67 |
12-18 | 0 | 0.6 | 0 | 0.6 | 1 | 1.8 | 1 | 1.2 | |
18-24 | 0 | 0.88 | 0 | 1 | 1.3 | 2.6 | 1.7 | 2.4 |
C=control Mice
++=QLα12LacZ+/Nphs2-Cre+ mice
FP=foot process
EFF=effacement
DC=double contours
MES=mesangial