Table 2.
Variable | All participants with asthma |
|
---|---|---|
Statistic | P | |
Age | ||
At time of study | −0.040 | 0.7205 |
At diagnosis | 0.003 | 0.9794 |
At symptom onset | 0.063 | 0.5821 |
Gender | ||
Male | 22.08 (19.173, 24.99) | 0.530 |
Female | 20.94 (19.159, 22.727) | |
Ethnicity | ||
Caucasian | 19.82 (17.591, 22.05) | 0.055 |
African American | 22.85 (20.672, 25.034) | |
Other | ||
BMI | −0.220 | 0.1131 |
Asthma history, percent | ||
Maternal | ||
No | 22.27 (18.532, 26.014) | 0.609 |
Yes | 20.87 (17.063, 24.689) | |
1st degree family member | ||
No | 22.69 (17.169, 28.213) | 0.573 |
Yes | 21.18 (18.196, 24.166) | |
Skin atopy | ||
No | 21.09 (15.567, 26.611) | 0.834 |
Yes | 20.47 (18.312, 22.634) | |
FEV1 | ||
Predicted, pre-BD | −0.024 | 0.8351 |
Predicted, post-BD | 0.010 | 0.9557 |
Change, post-BD | −0.201 | 0.2323 |
Change ≥ 12, post-BD | ||
No | 21.74 (19.032, 24.456) | 0.705 |
Yes | 20.87 (16.549, 25.191) | |
FVC | ||
Predicted, pre-BD | 0.028 | 0.8170 |
Predicted, post-BD | −0.159 | 0.3622 |
Change, post-BD | −0.277 | 0.1021 |
Change ≥ 12, post-BD | ||
No | 22.78 (20.545, 25.011) | 0.006 |
Yes | 14.31 (7.1749, 21.451) | |
FeNO | 0.072 | 0.6933 |
PC20 | −0.426 | 0.0879 |
Inhaled corticosteroid dose | 0.300 | 0.0322 |
Inflammatory cells | ||
Eosinophils – circulating | 0.347 | 0.0969 |
Eosinophils – sputum | 0.239 | 0.2610 |
Neutrophils - sputum | 0.265 | 0.1126 |
Pearson correlation coefficients are provided for associations between autoAb concentrations and continuous variables. Mean as well as upper and lower confidence limit intervals are provided for associations between autoAb concentrations and categorical variables. BD – bronchodilation. FEV1 – forced expiratory volume in one second. FVC – forced vital capacity. PC20 – provocative concentration of a substance (methacholine) capable of inducing a 20% decrease in FEV1. NA – analysis could not be performed