Table III.

Peak voxel values and coordinates for whole brain, voxelwise, statistical parametric maps of two‐way t‐tests between the Control Group (N = 21) and OTCD Group (N = 19), testing for activation correlated with an increase in working memory load

	Area	Talairach coordinates			T‐statistic	Uncorrected P‐value
		X	Y	Z
Control Group—OTCD Group
	No suprathreshold voxels
OTCD Group—Control Group
Cluster 1	4464 mm3
	R. Mid. Frontal G.	47	46	18	4.21	0.0000129
	R. Sup. Frontal G.	23	60	19	3.77	0.0000832
	R. Sup. Frontal G.	31	48	26	2.98	0.00145
Cluster 2	3856 mm3
	R. Cingulate G.	7	18	32	3.11	0.00095
	R. Cingulate G.	3	23	21	2.95	0.00159
	L. Cingulate G.	−9	25	28	2.79	0.00264
Cluster 3	1352 mm3
	R. Mid. Frontal G.	26	30	41	3.08	0.00102
Cluster 4	544 mm3
	R. Mid. Frontal G.	31	51	0	3.01	0.00132
Cluster 5	760 mm3
	R. Mid. Temporal G.	60	−24	−11	2.97	0.0015
Cluster 6	248 mm3
	L. Sup. Frontal G.	−30	53	23	2.94	0.00164
Cluster 7	664 mm3
	L. Cerebellum	−41	−68	−21	2.86	0.00211
Cluster 8	280 mm3
	R. Lingual G.	2	−78	−5	2.82	0.00238
Cluster 9	240 mm3
	L. Cerebellum	−11	−84	−16	2.79	0.00263

Clusters reported are for voxels surviving uncorrected P‐value < 0.005, minimum of 160 mm³ per cluster and peaks 4‐mm apart.