Table 4.
Summary of linear trend analysis for intensity estimates of menthol sensations for both nicotine stimulus conditions by menthol concentrations
| Menthol concentration | Low nicotine | High nicotine | ||||
|---|---|---|---|---|---|---|
| Odor | Cooling | Pain | Odor | Cooling | Pain | |
| Mean (95 % CI) | Mean (95 % CI) | Mean (95 % CI) | Mean (95 % CI) | Mean (95 % CI) | Mean (95 % CI) | |
| Low | 46.50 (40.73, 52.29) | 65.02 (59.83, 70.20) | 17.21 (12.82, 21.60) | 60.45 (54.11, 66.78) | 72.10 (66.61, 77.59) | 14.16 (11.09, 17.23) |
| Medium | 60.58 (55.07, 66.09) | 84.88 (79.95, 89.81) | 9.76 (5.58, 13.94) | 57.82 (51.31, 64.32) | 74.10 (68.47, 79.72) | 9.27 (6.12, 12.41) |
| High | 65.52 (59.91, 71.12) | 94.38 (89.37, 99.40) | 31.86 (27.56, 36.17) | 56.92 (50.40, 63.44) | 74.33 (68.69, 79.97) | 30.12 (26.93, 33.29) |
| P-trend | P < 0.0001 F = 21.49 | P < 0.0001 F = 63.91 | P < 0.0001 F = 21.91 | P = 0.45 F = 0.58 | P = 0.58 F = 0.31 | P < 0.0001 F = 50.26 |
Values shown as least-square mean (95 % confidence intervals). P values for trend were derived from a general linear model; statistical significance was evaluated at P < 0.05