Table 2.
Patients in the PD FOG group
| Patient | Age/sex | Parkinson’s disease duration (years) | Post-op duration (years, months) | Levodopa dose equivalent (mg/day) | UPDRS III OFF/ON meds (off stim) | IT27-30 off/on stim (OFF meds) | GFQ pre/ post-op | FOGQ pre/ post-op | FallsQ pre/ post-op | Supportive for UK brain bank criteriaa |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 61F | 10 | 2 | 800 | 40/23 | 10/9 | 61/36 | 24/16 | 4/3 | D, A, P |
| 2 | 72M | 18 | 2, 5 | 2500 | 25/17 | 6/6 | 30/16 | 14/11 | 4/2 | D, A, T, P |
| 3 | 76M | 6 | 2 | 600 | 26/14 | 6/4 | 51/18 | 22/7 | 3/3 | A, P |
| 4 | 72F | 10 | 2 | 950 | 38/22 | 11/8 | 48/26 | 22/13 | 4/2 | D, A, T, P |
| 5 | 77M | 6 | 0, 6 | 1400 | 31/17 | 10/10 | 31/14 | ^/6 | ^/2 | A, P |
| 6 | 55M | 20 | 1 | 850 | 51/19 | 8/6 | 38/40 | 14/15 | 4/4 | D, A, T, P |
| 7 | 55M | 14 | 0, 2 | 1650 | 34/24 | 7/4 | 55/37 | 22/16 | 4/4 | A, P |
Postoperative clinical assessments were performed on the same day as gait analysis. Patients 6 and 7 were from Oxford, other patients from Brisbane. Patient 6 also had subthalamic nucleus stimulators, which were turned off during experiments.
a Additional to disease duration and levodopa response as documented elsewhere in the table. Reaction time data of Patients 1–6 and 2-year clinical scores of Patients 1–4 have been reported previously.
^ = not known; Key to UK Brain bank criteria: D = dyskinesias; A = asymmetry persistent; T = tremor at rest; P = progressive disease course; UPDRS III = part III (motor) Unified Parkinson’s disease rating scale (score/108); IT27-30 = items 27–30 of Unified Parkinson’s disease rating scale, assessing gait, posture and balance (score/16); GFQ = Gait and Falls Questionnaire (score/64); FOGQ = Freezing of Gait Questionnaire (score/24); FallsQ = Falls Question (score/4).