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Odds ratios for hepatocellular carcinoma, according to alcohol intake and the presence of hepatitis B virus (HBV) or hepatitis C virus (HCV) infection. The plot was obtained by fitting spline regression models on data obtained in Brescia, Italy, 1995–2000. (modified from Donato F et al. Am. J. Epidemiol. 2002;155:323-331)
