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. Author manuscript; available in PMC: 2012 Apr 29.
Published in final edited form as: J Am Chem Soc. 2012 Mar 16;134(12):5689–5696. doi: 10.1021/ja300839n

Figure 3.

Figure 3

The pinwheel effect allows for quantification of DNA and cell counting. (A) Calibration curve illustrating the relationship between the mass of prepurified DNA and the extent of pinwheel formation (% Dark Area). The solid line represents a stretched exponential calibration function fitted to the data; the shaded area and green lines show the 95% and 90% confidence regions for this fit. (B) Pinwheel calibration curves for DNA from bacteriophage M13 (size 6.4 kbp), lambda phage DNA (48.5 kbp), and DNA in human whole blood (~100 kbp).