Table 3.

Agreement between Gleason patterns and scores assigned by final expert review and those documented in pathology reports

A. BIOPSY SPECIMENS (n=264)
						Pathology Report
		1+2=3	3+3=6	3+4=7	4+3=7	3+5=8	4+4=8	5+3=8	4+5=9	5+4=9	5+5=10
Final Expert Review	1+2=3	0	0	0	0	0	0	0	0	0	0
	3+3=6	0	87	5	0	0	0	0	0	0	0
	3+4=7	0	43	40	8	1	1	0	0	1	0
	4+3=7	1	7	14	4	0	8	0	1	1	0
	3+5=8	0	0	0	0	0	0	0	1	0	0
	4+4=8	0	1	4	2	0	9	0	3	0	0
	5+3=8	0	0	0	0	0	0	0	0	0	0
	4+5=9	0	0	2	1	0	5	1	8	1	3
	5+4=9	0	0	0	0	0	0	0	0	0	1
	5+5=10	0	0	0	0	0	0	0	0	0	0
	Weighted kappa for Gleason patterns: 0.61 (95% CI: 0.54, 0.68)
	Weighted kappa for total Gleason score: 0.60 (95% CI: 0.53, 0.67)
	Kappa for Gleason score ≤7 versus ≥8: 0.58 (95% CI: 0.48, 0.67)

B. PROSTATECTOMY SPECIMENS (n=120)
					Pathology Report
		3+2=5	2+4=6	3+3=6	3+4=7	4+3=7	3+5=8	4+4=8	4+5=9	5+4=9	5+5=10
Final Expert Review	3+2=5	0	0	0	0	0	0	0	0	0	0
	2+4=6	0	0	0	0	0	0	0	0	0	0
	3+3=6	1	0	36	6	0	0	0	1	0	0
	3+4=7	1	1	24	24	0	2	1	1	0	1
	4+3=7	0	0	2	9	1	0	1	1	0	0
	3+5=8	0	0	0	2	0	0	0	0	0	0
	4+4=8	0	0	0	0	0	0	1	0	0	0
	4+5=9	0	0	0	1	0	0	2	0	1	0
	5+4=9	0	0	0	0	0	0	0	0	0	0
	5+5=10	0	0	0	0	0	0	0	0	0	0
	Weighted kappa for Gleason patterns: 0.37 (95% CI: 0.23, 0.51)
	Weighted kappa for total Gleason score: 0.38 (95% CI: 0.26, 0.51)
	Kappa for Gleason score ≤ 7 versus ≥8: 0.43 (95% CI: 0.28, 0.58)