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Immunohistochemical evaluation after HSV-2 challenge. After inoculation of wild-type HSV-2 strain 186 into HF10-immunized mice or unimmunized mice vagina; vaginal mucosal lesions were excised at days 1, 4, and 6 after challenge, and HSV-2 antigens were stained. Arrows indicate HSV-2-infected cells.
