Table 3.
Adjusted regression coefficients [β (95% CI)] between electrophysiological tests and pesticide use (ever use and log10 lifetime days of use) among 678 male pesticide applicators in the AHS.
| Exposure | Distal motor amplitude (mV; n = 664) | Distal motor latency (msec; n = 655)a | Nerve conduction velocity (m/sec; n = 652) | Short F-wave latency (msec; n = 544)a |
|---|---|---|---|---|
| OPs | ||||
| Acephate | ||||
| Ever use | 0.01 (–0.53, 0.54) | 0.03 (–0.14, 0.20) | 0.42 (–0.42, 1.27) | 1.18 (0.20, 2.16) |
| Lifetime days | 0.05 (–0.24, 0.34) | 0.02 (–0.07, 0.11) | 0.22 (–0.24, 0.68) | 0.73 (0.21, 1.25) |
| Chlorpyrifos | ||||
| Ever use | 0.05 (–0.33, 0.43) | –0.07 (–0.20, 0.05) | 0.12 (–0.48, 0.73) | 0.09 (–0.60, 0.79) |
| Lifetime days | –0.02 (–0.24, 0.19) | –0.01 (–0.08, 0.05) | 0.18 (–0.16, 0.53) | 0.11 (–0.28, 0.50) |
| Coumaphos | ||||
| Ever use | –0.09 (–0.64, 0.46) | –0.04 (–0.22, 0.13) | 0.35 (–0.53, 1.24) | 0.36 (–0.64, 1.37) |
| Lifetime days | –0.05 (–0.43, 0.34) | –0.01 (–0.14, 0.11) | 0.25 (–0.37, 0.87) | 0.00 (–0.68, 0.68) |
| Diazinon | ||||
| Ever use | 0.04 (–0.34, 0.42) | –0.12 (–0.24, 0.00) | 0.07 (–0.54, 0.68) | 0.09 (–0.61, 0.80) |
| Lifetime days | 0.08 (–0.16, 0.33) | –0.07 (–0.15, 0.00) | 0.07 (–0.33, 0.46) | 0.16 (–0.32, 0.58) |
| Dichlorvos | ||||
| Ever use | –0.31 (–0.82, 0.20) | –0.15 (–0.32, –0.01) | –0.14 (–0.96, 0.67) | –0.66 (–1.57, 0.26) |
| Lifetime days | –0.03 (–0.27, 0.21) | –0.05 (–0.13, 0.02) | –0.11 (–0.49, 0.27) | –0.27 (–0.70, 0.15) |
| Dimethoate | ||||
| Ever use | 0.23 (–0.40, 0.86) | –0.02 (–0.21, 0.18) | –0.07 (–1.07, 0.92) | –0.04 (–1.20, 1.12) |
| Lifetime days | 0.10 (–0.33, 0.52) | –0.01 (–0.15, 0.12) | –0.01 (–0.68, 0.66) | –0.08 (–0.86, 0.70) |
| Disulfoton | ||||
| Ever use | 0.03 (–0.53, 0.59) | 0.07 (–0.11, 0.25) | –0.40 (–1.30, 0.49) | 0.57 (–0.47, 1.61) |
| Lifetime days | 0.01 (–0.35, 0.37) | 0.03 (–0.09, 0.14) | –0.22 (–0.80, 0.36) | 0.46 (–0.21, 1.14) |
| Ethoprop | ||||
| Ever use | –0.41 (–0.95, 0.12) | –0.08 (–0.25, 0.09) | –0.60 (–1.45, 0.24) | –0.01 (–1.01, 0.99) |
| Lifetime days | –0.28 (–0.62, 0.07) | –0.06 (–0.17, 0.05) | –0.36 (–0.91, 0.19) | –0.08 (–0.72, 0.57) |
| Fonofos | ||||
| Ever use | 0.05 (–0.40, 0.50) | –0.09 (–0.24, 0.05) | 0.09 (–0.63, 0.81) | –0.09 (–0.91, 0.73) |
| Lifetime days | 0.06 (–0.21, 0.33) | –0.04 (–0.13, 0.04) | –0.04 (–0.48, 0.39) | –0.05 (–0.54, 0.44) |
| Malathion | ||||
| Ever use | 0.28 (–0.16, 0.72) | –0.02 (–0.16, 0.12) | –0.09 (–0.79, 0.61) | –0.70 (–1.51, 0.11) |
| Lifetime days | –0.03 (–0.25, 0.19) | –0.05 (–0.12, 0.02) | 0.01 (–0.34, 0.36) | –0.27 (–0.67, 0.14) |
| Parathion | ||||
| Ever use | 0.22 (–0.25, 0.68) | –0.07 (–0.22, –0.08) | –0.01 (–0.75, 0.73) | 0.31 (–0.53, 1.15) |
| Lifetime days | 0.25 (–0.04, 0.54) | 0.01 (–0.08, 0.10) | 0.03 (–0.43, 0.49) | 0.17 (–0.34, 0.68) |
| Phorate | ||||
| Ever use | 0.47 (0.06, 0.88) | 0.01 (–0.13, 0.14) | 0.64 (–0.01, 1.29) | 0.91 (0.16, 1.66) |
| Lifetime days | 0.28 (0.04, 0.52) | 0.01 (–0.06, 0.09) | 0.51 (0.12, 0.89) | 0.73 (0.29, 1.17) |
| Phosmet | ||||
| Ever use | –0.07 (–0.63, 0.49) | –0.05 (–0.23, 0.13) | –0.21 (–1.11, 0.69) | –0.27 (–1.30, 0.75) |
| Lifetime days | –0.09 (–0.43, 0.25) | –0.01 (–0.13, 0.10) | –0.10 (–0.65, 0.46) | –0.04 (–0.68, 0.59) |
| Tebupirimfos | ||||
| Ever use | 0.71 (0.05, 1.37) | 0.06 (–0.15, 0.27) | 0.78 (–0.28, 1.84) | –0.05 (–1.24, 1.13) |
| Lifetime days | 0.43 (0.02, 0.84) | 0.04 (–0.09, 0.17) | 0.51 (–0.14, 1.17) | 0.08 (–0.65, 0.80) |
| Terbufos | ||||
| Ever use | 0.20 (–0.18, 0.59) | 0.05 (–0.07, 0.17) | 0.21 (–0.41, 0.82) | 0.16 (–0.54, 0.86) |
| Lifetime days | 0.14 (–0.06, 0.34) | 0.04 (–0.03, 0.10) | 0.18 (–0.15, 0.51) | 0.30 (–0.07, 0.67) |
| Tetrachlorvinphos | ||||
| Ever use | –0.40 (–1.03, 0.24) | –0.05 (–0.24, 0.15) | –0.04 (–1.06, 0.99) | –0.36 (–1.50, 0.77) |
| Lifetime days | –0.23 (–0.62, 0.16) | –0.02 (–0.14, 0.10) | 0.15 (–0.47, 0.77) | –0.13 (–0.81, 0.56) |
| Carbamates | ||||
| Aldicarb | ||||
| Ever use | 0.30 (–0.22, 0.83) | –0.06 (–0.22, 0.11) | –0.61 (–0.23, 1.44) | 1.73 (0.74, 2.71) |
| Lifetime days | 0.18 (–0.12, 0.49) | –0.06 (–0.16, 0.03) | 0.27 (–0.21, 0.75) | 0.87 (0.31, 1.44) |
| Benomyl | ||||
| Ever use | 0.28 (–0.26, 0.82) | –0.06 (–0.23, 0.11) | 0.62 (–0.23, 1.48) | 0.60 (–0.40, 1.60) |
| Lifetime days | 0.11 (–0.24, 0.47) | –0.07 (–0.18, 0.04) | 0.44 (–0.12, 1.00) | 0.39 (–0.27, 1.05) |
| Carbaryl | ||||
| Ever use | –0.10 (–0.54, 0.33) | –0.13 (–0.26, 0.01) | –0.30 (–0.99, 0.40) | –0.62 (–1.40, 0.16) |
| Lifetime days | 0.08 (–0.16, 0.33) | –0.10 (–0.18, –0.02) | –0.01 (–0.41, 0.38) | –0.31 (–0.76, 0.13) |
| Carbofuran | ||||
| Ever use | –0.03 (–0.41, 0.35) | –0.07 (–0.20, 0.04) | –0.18 (–0.78, 0.43) | –0.30 (–0.99, 0.40) |
| Lifetime days | 0.00 (–0.24, 0.23) | –0.04 (–0.11, 0.04) | 0.03 (–0.35, 0.41) | –0.08 (–0.52, 0.36) |
| Summary variables | ||||
| Lifetime days to all OPs | 0.22 (–0.06, 0.49) | –0.02 (–0.10, 0.07) | 0.31 (–0.12, 0.74) | 0.53 (0.02, 1.02) |
| Lifetime days to all pesticides | 0.19 (–0.19, 0.58) | 0.10 (–0.22, 0.02) | 0.53 (–0.08, 1.14) | 0.75 (0.01, 1.50) |
| HPEEs (ever) | 0.54 (0.10, 0.98) | –0.01 (–0.15, 0.13) | 0.02 (–0.68, 0.72) | 0.16 (–0.63, 0.96) |
| Electrophysiological tests were adjusted for age, height, foot temperature, and state. aScores have been multiplied by –1 so that lower scores indicate poorer test results. | ||||