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. 2011 Dec 8;18(5):265–279. doi: 10.1093/molehr/gar078

Figure 7.

Figure 7

ROCK inhibitor g-H-1152 causes disassembly of actin stress fibres in cultured myometrial cells. Representative examples of filamentous actin (F-actin) staining with Alexa Fluor 488® -phalloidin in resting myometrial cells; (A) in the absence of inhibitors or (B) in the presence of 1 µM ROCK inhibitor g-H-1152 or (C) 2 µM PKC inhibitor bisindolylmaleimide I (BIS1). Nuclear DNA was detected with DAPI (blue in insets). Wide-field images show decreases in overall F-actin staining (white) with ROCK inhibition, and insets highlight the parallel stress fibre bundles (green) in cells which decrease in the presence of ROCK inhibitor g-H-1152. Scale bars = 500 and 50 µm in insets.