Table 1.
Commonly up-regulated genes in the central area vs. the peripheral area of the thyroid
| GenBank | Gene symbol | Description | Fold change | P value |
|---|---|---|---|---|
| NM_018866 | Cxcl13 | Chemokine (C-X-C motif) ligand 13 (Cxcl13) | 4.8165902 | 0.0004 |
| NM_007587 | Calca | Calcitonin/calcitonin-related polypeptide, α | 4.5885531 | 0.0024 |
| NM_030725 | Syt13 | Synaptotagmin XIII (Syt13) | 4.3638275 | 0.001 |
| NM_009130 | Scg3 | Secretogranin III (Scg3) | 4.2596294 | 0.0002 |
| NM_013628 | Pcsk1 | Proprotein convertase subtilisin/kexin type 1 | 4.0102517 | 0.0016 |
| NM_007694 | Chgb | Chromogranin B (Chgb) | 3.9725184 | 0.0003 |
| NM_007693 | Chga | Chromogranin A (Chga) | 3.9549664 | 0.0005 |
| NM_152915 | Dner | δ/Notch-like EGF-related receptor (Dner) | 3.9470842 | 0.0013 |
| NM_010446 | Foxa2 | Forkhead box A2 (Foxa2) | 3.9079868 | 0.0004 |
| AK129109 | Trim9 | mKIAA0282 protein | 3.8122757 | 0.0041 |
| NM_010461 | Hoxb8 | Homeo box B8 (Hoxb8) | 3.5424765 | 0.0074 |
| NM_008792 | Pcsk2 | Proprotein convertase subtilisin/kexin type 2 | 3.425516 | 0.0001 |
| BC042620 | Fbxl16 | F-box and leucine-rich repeat protein 16 | 3.4076878 | 0.0072 |
| NM_011510 | Abcc8 | ATP-binding cassette, subfamily C (CFTR/MRP), member 8 (Abcc8) | 3.2616852 | 0.0008 |
| NM_010932 | Pnoc | Prepronociceptin | 3.257574 | 0 |
| NM_001024698 | Cpa2 | Similar to Carboxypeptidase A2 precursor (MGC107514) | 3.1251535 | 0.0214 |
| NM_007467 | Aplp1 | Amyloid β (A4) precursor-like protein 1 | 3.091298 | 0.0003 |
| NM_007709 | Cited1 | Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 | 3.0654408 | 0.0003 |
| AK030625 | Gpr179 | Adult male pituitary gland cDNA, RIKEN full-length enriched library, clone:5330439C02 product:hypothetical protein | 3.0615862 | 0.0001 |
| NM_027539 | Dclk2 | Doublecortin and CaM kinase-like 2 (Dcamkl2) | 2.9675104 | 0.0009 |
| NM_144926 | Sez6l2 | Seizure related 6 homolog (mouse)-like 2 | 2.928459 | 0.0004 |
| NM_007675 | Ceacam10 | CEA-related cell adhesion molecule 10 | 2.8990497 | 0.0076 |
| NM_009049 | Resp18 | Regulated endocrine-specific protein 18 | 2.8595104 | 0.0007 |
| NM_144891 | Gdap1l1 | Ganglioside-induced differentiation-associated protein 1-like 1 | 2.8063135 | 0.001 |
| AK220449 | Lhfpl4 | mKIAA4027 protein | 2.7361495 | 0.0012 |
| NM_178676 | Entpd3 | Ectonucleoside triphosphate diphosphohydrolase 3 | 2.6888210 | 0.0017 |
| NM_009513 | Nrsn1 | Vesicular membrane protein p24 (Vmp) | 2.6829494 | 0.0003 |
| NM_007866 | Dll3 | δ-Like 3 (Drosophila) (Dll3), transcript variant 1 | 2.6579014 | 0.0005 |
| NM_009022 | Aldh1a2 | Aldehyde dehydrogenase family 1, subfamily A2 | 2.5968126 | 0.0012 |
| NM_025869 | Dusp26 | Dual specificity phosphatase 26 (putative) | 2.5442488 | 0.0003 |
| NM_008101 | Gcgr | Glucagon receptor | 2.5138046 | 0.0006 |
Only genes with known gene symbols that were up-regulated more than 2-fold in log2 scale in the center parts of both normal and dissected thyroids as compared with the peripheral areas are listed. Values shown are those obtained with dissected thyroids.