Table 2.
Most significantly differentially expressed genes between DA.ACI(Cia10) congenics and DA.
| Gene symbol | Gene name | Accession number | Fold difference | P-value |
|---|---|---|---|---|
| Up-regulated in DA | DA/Cia10 | |||
| LOC499078 | similar to glycoprotein 49b | GI_62638899-S | 5.39 | 0.0023 |
| Cd53 | cluster of differentiation 53 | NM_012523.1 | 3.28 | 0.0040 |
| RGD1566002 | similar to RIKEN cDNA 3110001N18 | XM_221003.3 | 3.09 | 0.0038 |
| Fcgr1a | Fc fragment of IgG, high affinity Ia, receptor (CD64) | XM_001062370.1 | 2.94 | 0.0073 |
| ccdc109b | coiled-coil domain containing 109B | XM_001076863.1 | 2.89 | 0.0036 |
| LOC499136 | hypothetical gene | XM_574429.1 | 2.85 | 0.0014 |
| Rangap1 | RAN GTPase activating protein 1 | XM_576313.1 | 2.84 | 0.0051 |
| RGD1565520 | similar to 60S ribosomal protein L7a | XR_009158.1 | 2.81 | 0.0025 |
| Emr1 | egf-like module containing mucin like hormone receptor | NM_001007557.1 | 2.78 | 0.0000 |
| LOC308350 | similar to PIRB1 | XM_218261.3 | 2.73 | 0.0074 |
| RGD1564866 | similar to Heterogeneous nuclear ribonucleoprotein A1 | XR_007647.1 | 2.72 | 0.0038 |
| LOC687849 | hypothetical gene | XM_001080339.1 | 2.69 | 0.0012 |
| Rbbp7 | Retinoblastoma-binding protein 7 | NM_031816.1 | 2.68 | 0.0052 |
| RGD1563503 | similar to ribosomal protein L6 | XR_007388.1 | 2.67 | 0.0010 |
| RGD1563124 | similar to 40S ribosomal protein S20 | XM_576204.2 | 2.66 | 0.0013 |
| RGD1559935 | similar to Selenoprotein H | XR_008210.1 | 2.66 | 0.0027 |
| Ppid | peptidylprolyl isomerase D | NM_001004279.1 | 2.66 | 0.0003 |
| RGD1560979 | hypothetical gene | XR_008629.1 | 2.65 | 0.0031 |
| Acsl4 | acyl-CoA synthetase long-chain family member 4 | NM_053623.1 | 2.62 | 0.0033 |
| St14 | suppression of tumorigenicity 14 | NM_053635.2 | 2.55 | 0.0004 |
| Shc1 | Src homology 2 domain-containing transforming protein C1 | NM_053517.1 | 2.55 | 0.0001 |
| LOC306428 | similar to Chain A, T13s Mutant Of Bovine 70 Kilodalton Heat Shock Protein | XM_224824.3 | 2.55 | 0.0007 |
| LOC316373 | similar to high-mobility group (nonhistone chromosomal) protein 1-like 1 | XR_007934.1 | 2.54 | 0.0064 |
| Fcgr3a | Fc receptor, IgG 3a | NM_207603.1 | 2.51 | 0.0021 |
| Rsl1d1 | ribosomal L1 domain containing 1 | NM_001008876.1 | 2.50 | 0.0032 |
| Matk | megakaryocyte-associated tyrosine kinase | NM_021859.2 | 2.49 | 0.0044 |
| RGD1559682 | similar to peptidylprolyl isomerase A | XM_001075526.1 | 2.47 | 0.0042 |
| Fcgr2b | Fc fragment of IgG, low affinity IIb, receptor (CD32) | NM_175756.1 | 2.45 | 0.0090 |
| Smc4l1 | structural maintenance of chromosomes 4 | XM_001066172.1 | 2.43 | 0.0059 |
| Tnfaip8l2 | Tumor necrosis factor, alpha-induced protein 8-like 2 | NM_001014039.1 | 2.42 | 0.0095 |
| Psmb9 | proteasome subunit beta-1i | NM_012708.1 | 2.41 | 0.0002 |
| RGD620382 | Nucleoside 2-deoxyribosyltransferase domain containing protein | NM_133525.1 | 2.38 | 0.0037 |
| RGD1565238 | similar to Gapdh | XM_001081651.1 | 2.37 | 0.0097 |
| RGD1565306 | similar to 60S ribosomal protein L29 | XM_576023.2 | 2.35 | 0.0064 |
| Up-regulated in DA.ACI(Cia10) | Cia10/DA | |||
| LOC259244 | alpha-2u globulin PGCL3 | NM_147212.1 | 5.01 | 0.0067 |
| Mup4 | alpha-2u globulin PGCL3 | NM_198784.1 | 4.88 | 0.0067 |
| LOC682605 | alpha-2u globulin PGCL3 | XM_001062261.1 | 4.32 | 0.0074 |
| MGC72973 | beta-globulin | NM_198776.1 | 3.71 | 0.0095 |
| Aldh1a1 | aldehyde dehydrogenase 1 family, member A1 | NM_022407.3 | 3.70 | 0.0090 |
| Rpesp | RPE-spondin | XM_001063197.1 | 3.56 | 0.0082 |
| Igfbp6 | insulin-like growth factor binding protein 6 | NM_013104.2 | 3.56 | 0.0068 |
| Ccdc3 | colied coil domain containing 3 | XM_574081.1 | 3.44 | 0.0097 |
| Mt3 | metallothionein 3 | NM_053968.2 | 3.34 | 0.0089 |
| RGD1310507 | similar to RIKEN cDNA 1300017J02 | XM_236574.4 | 3.27 | 0.0072 |
| Fxyd6 | FXYD domain-containing ion transport regulator 6 | NM_022005.1 | 3.26 | 0.0090 |
| Cav2 | caveolin 2 | NM_131914.2 | 3.02 | 0.0058 |
| Fhl1 | four and a half LIM domains protein 1 | NM_145669.2 | 3.01 | 0.0086 |
| Nov | nephroblastoma overexpressed gene | NM_030868.2 | 2.86 | 0.0070 |
| Per1 | period 1 | XM_340822.2 | 2.78 | 0.0011 |
| Myh11 | myosin, heavy chain 11, smooth muscle | XM_573030.2 | 2.77 | 0.0057 |
| Gstm2 | glutathione S-transferase, mu 2 | NM_177426.1 | 2.71 | 0.0028 |
| Klhl23 | similar to 60S ribosomal protein L7a | XM_001059088.1 | 2.60 | 0.0007 |
| Pcsk1n | proprotein convertase subtilisin/kexin type 1 inhibitor | NM_019279.1 | 2.58 | 0.0072 |
| Gstm1 | glutathione S-transferase, mu 1 | NM_017014.1 | 2.58 | 0.0029 |
| Hbb | hemoglobin, beta | NM_033234.1 | 2.55 | 0.0063 |
| Etl4 | enhancer trap locus 4 | XM_001069190.1 | 2.48 | 0.0069 |
| Ctnnal1 | catenin (cadherin associated protein), alpha-like 1 | XM_001059679.1 | 2.36 | 0.0077 |
| Sptbn1 | spectrin, beta, non-erythrocytic 1 | NM_001013130.1 | 2.24 | 0.0041 |
| Cyb5r1 | cytochrome b5 reductase 1 | NM_001013126.1 | 2.20 | 0.0010 |
| Timp2 | tissue inhibitor of metalloproteinases-2 | NM_021989.2 | 2.15 | 0.0024 |
| LOC500248 | similar to 1300014I06Rik protein | XM_580052.1 | 2.14 | 0.0078 |
| Reck | reversion-inducing-cysteine-rich protein with kazal motifs | XM_001070551.1 | 2.10 | 0.0050 |
| Cldn22 | claudin 22 | XM_224843.2 | 2.10 | 0.0019 |
| Ddit4 | DNA-damage-inducible transcript 4 | NM_080906.1 | 2.09 | 0.0090 |
| RGD1311307 | similar to 1300014I06Rik protein | NM_001025719.1 | 2.08 | 0.0074 |
| Cat | catalase | NM_012520.1 | 2.07 | 0.0076 |
| Tmem117 | transmembrane protein 117 | XM_576330.2 | 2.06 | 0.0023 |
| Nes | nestin | NM_012987.1 | 2.06 | 0.0060 |
| Rgs4 | regulator of G-protein signaling 4 | NM_017214.1 | 2.05 | 0.0079 |
| Hexim1 | hexamethylene bis-acetamide inducible 1 | XM_573204.1 | 2.04 | 0.0022 |
| Axl | AXL receptor tyrosine kinase | NM_001013147.1 | 2.03 | 0.0046 |
| Tspan2 | tetraspanin-2 | NM_022589.1 | 2.02 | 0.0057 |