Table 4.
Associations of hormones with time to menopause
| Hormone | Unadjusted |
Adjustedc |
||||
|---|---|---|---|---|---|---|
| Hazard ratiob | 95% CI | P | Hazard ratioc | 95% CI | P | |
| log AMH (ng/ml)a | 0.44 | 0.38–0.52 | <0.0001 | 0.56 | 0.47–0.67 | <0.0001 |
| log FSH (mIU/ml)a | 1.44 | 1.27–1.64 | <0.0001 | 1.19 | 1.05–1.36 | 0.007 |
| log Inhibin b (pg/ml)a | 0.66 | 0.58–0.76 | <0.0001 | 0.79 | 0.68–0.92 | 0.003 |
a
Natural log of hormone as a continuous variable.
b
Hazard ratio indicates risk of menopause for each 1 sd increase in the log hormone. Hazard ratios greater than 1 indicate increased risk of menopause with each sd increase in the log hormone values (i.e. FSH). Hazard ratios less than 1 indicate a decreasing risk of menopause for each sd increase in log hormone values (AMH, inhibin b).
c
Adjusted for age, smoking, race. Each hormone entered singly due to high correlation of hormones in the adjusted models.