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. 2012 Mar 1;53(3):1117–1129. doi: 10.1167/iovs.11-8168

Figure 1.

Figure 1.

Impaired rod and rod-driven ERG responses in CNGA3−/− mice. Scotopic ERG recordings were performed in CNGA3−/− and wild-type (WT) mice at varying postnatal ages, from 1 to 12 months. (A) Scotopic a-wave (left) and b-wave (right) amplitude in CNGA3−/− and WT mice. Data are represented as mean ± SEM (n = 8 to 12 mice for each group) (*P < 0.05). (B). Representative waveforms of scotopic ERG recordings to serial stimuli at increasing intensities from CNGA3−/− and WT mice at 1 and 12 months. (C). Scotopic ERG a-wave (left) and b-wave (right) amplitude in response to stimulus of increasing intensity from CNGA3−/− and WT mice at 1 and 12 months. Data are represented as mean ± SEM (n = 4 to 5 mice for each group) (*P < 0.05, compared with WT mice at 12 months; X, P < 0.05, compared with WT mice at 1 month).