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. 2012 Mar 9;53(3):1244–1250. doi: 10.1167/iovs.11-8668

Figure 3.

Figure 3.

Trafficking of APCs to draining lymph nodes after corneal transplantation is suppressed by anti-VEGF-C. Percentage of CD11b+ APCs in ipsilateral draining lymph nodes of transplanted corneas evaluated at different time points (days 1, 3, 7, and 14 post-transplant) by flow cytometry. APC content of the draining lymph nodes is significantly increased at day 1 after transplantation and returns to normal levels by day 3. Administration of anti-VEGF-C antibody significantly blocked the early rise in the APC content of draining lymph nodes. Results represent mean ± SEM of five samples per group (**P < 0.01 compared with control).