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. 2012 Mar 9;53(3):1244–1250. doi: 10.1167/iovs.11-8668

Figure 6.

Figure 6.

VEGF-C blockade promotes corneal allotransplant survival. In a masked fashion, orthotopically transplanted corneas from C57BL/6 (Iab) to BALB/c (Iad) mice were examined biomicroscopically and scored using a grading system designed to detect rejection for 8 weeks after transplantation. The fate of corneal graft is reported by Kaplan–Meier survival curves. VEGF-C blockade reduced the graft rejection rate and markedly improved graft survival from 33% in the control group to 66% in the anti-VEGF-C–treated group (n = 20 per group; *P < 0.05).