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. 2012 Mar 21;53(3):1548–1556. doi: 10.1167/iovs.11-8657

Table 3.

MAFs of SNPs in Progressors and Nonprogressors at Each Transition

SNP Gene Transition Minor Allele 1 → 2
2 → 3
3 → 4
3 → 5
Non* Pro* Non* Pro* Non* Pro* Non* Pro*
Subjects, n 219 494 814 376 949 280 949 298
rs1061170 CFH C 0.37 0.39 0.36 0.43 0.44 0.62 0.44 0.62
rs10490924 ARMS2/HTRA1 T 0.17 0.21 0.20 0.28 0.28 0.41 0.28 0.41
rs9332739 C2 C 0.06 0.05 0.05 0.04 0.04 0.02 0.04 0.02
rs641153 CFB T 0.11 0.09 0.09 0.07 0.08 0.05 0.08 0.04
rs2230199 C3 G 0.19 0.21 0.20 0.25 0.24 0.32 0.24 0.31
rs10033900 CFI T 0.45 0.51 0.49 0.49 0.49 0.57 0.49 0.49
rs10468017 LIPC T 0.34 0.29 0.28 0.28 0.29 0.24 0.29 0.26
rs9621532 TIMP3 C 0.06 0.05 0.05 0.06 0.06 0.04 0.06 0.04
rs3764261 CETP A 0.31 0.34 0.33 0.35 0.34 0.33 0.34 0.39
rs1883025 ABCA1 T 0.32 0.24 0.26 0.21 0.24 0.24 0.24 0.25
rs13095226 COL8A1 C 0.09 0.11 0.11 0.07 0.08 0.14 0.08 0.12
APOE APOE E4 0.14 0.13 0.12 0.10 0.12 0.09 0.12 0.10
*

Nonprogressors (Non) groups and progressors (Pro) for each transition in the five-state Markov model.

APOE haplotypes were defined by alleles in rs7412 and rs429358.