TABLE 1.

Structural statistics of 20 conformers of Dph4

Total restraints	1761
Distance restraints (upper limit)
All	1558
NOE intraresidue	478
Short range	461
Medium range	271
Long range	223
Hydrogen bonds	116
Zinc distance restraints	9
Dihedral angle constraints (°)
ϕ	104
ψ	99
Mean CYANA target function	2.13 ± 0.92
Ramachandran plot statistics: all residues (selected residuesa) (%)
Most favored regions	74.7 (86.3)
Additionally allowed regions	22.1 (13.5)
Generously allowed regions	2.2 (0.2)
Disallowed regions	1.0 (0.0)
r.m.s. deviation values (Å)b
N-terminal domain
Residues 11–72	1.53 ± 0.40
Helix 1 (residues 11–16)	0.27 ± 0.15
Helix 2 (residues 24–38)	0.39 ± 0.17
Helix 3 (residues 50–68)	0.52 ± 0.20
Linker (residues 76–93)
Helix 5 (residues 77–88)	0.15 ± 0.06
C-terminal domain
Residues 94–149	1.05 ± 0.28
Ordered residues (95–98, 103–105, 110–114, 120–124, 127–130, 133–135, and 142–146)	0.62 ± 0.14

^a Selected residues were as follows: 12–38, 50–69, 71–74, 77–90, 95–117, 120–137, and 142–146. Ramachandran plot statistics were obtained using PROCHECK. The residues observed in disallowed regions (1%) belonged to loop regions.

^b r.m.s. deviations were evaluated using MOLMOL.