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. 2012 Feb 24;287(16):12691–12702. doi: 10.1074/jbc.M111.316307

FIGURE 7.

FIGURE 7.

Model for the positive regulation of NPC migration by PACAP/Gs/PKA signal-induced DCX phosphorylation. DCX is phosphorylated by PKA, and the phosphorylated DCX is released from microtubules and interacts with Asef2. The resultant activation of Rac1 induces lamellipodia, which promote NPC migration.