FIGURE 3.

FGF21 increases LDLR and Cnpy2/Msap in cells. Cells were treated as below. Left, immunoblots; Right, quantification. Values are means ± S.D., n = 3. *, p < 0.05 and **, p < 0.01 for FGF21 versus C. A and B, raw cells were treated with 50 ng/ml FGF21 for different times and LDLR (A) and Cnpy/Msap (B) levels were determined by immunoblots. β-Actin was used as control. LDLR levels. Left, immunoblots; Right, quantification. C and D, Huh7 cells were treated for 24 h using different FGF21 concentrations followed by immunblotting using LDLR (C) and Cnpy2/Msap (D) antibodies.