Fig. 2.
(A and B) Luciferase reporter assays of rs62527607. Luciferase reporter constructs containing rs62527607 were transfected in triplicate into murine neuroblastoma cells (Neuro2a). Luciferase expression levels were normalized using a cotransfected Renilla construct (±SD). rs62527607 revealed activating potential compared with empty vectors without (pGL4.11) (A) and with promoter (pGL4.24) (B). The activating potential of rs62527607[T] is greater than that of rs62527607[G] [pGL4.11: P = 0.02 (A); pGL4.24: P = 4.31 × 10−3 (B)].