Table 7.
Relative hemolysis of epoprostenol formulations
| Diluent | Hemolysis (%) CMH procedure |
Hemolysis (%) Normal saline procedure |
|---|---|---|
| Epoprostenol AM reconstituted in SWI | 0.2 | 0.1 |
| Epoprostenol AM reconstituted in SSI | 0.0 | 0.0 |
| Flolan diluent (placebo) | 0.1 | 0.0 |
| Normal saline adjusted with 60 μg NaOH/100 mL saline | 0.0 | 0.0 |
| Normal saline adjusted to pH 13 | 0.3 | 0.1 |
| Plain blood (control) | 0.0 | 0.0 |
Abbreviations: AM, arginine and mannitol; SWI, sterile water for injection; SSI, sterile saline (sodium chloride 0.9%) for injection; NaOH, sodium hydroxide; CMH, cyanmethemoglobin.