Table 3.
Clinicopathologic survival and DCLK1 immunostaining characteristics in 40 colorectal adenocarcinomas
| Age at diagnosis | Gender | Primary tumor location | Pathology | AJCC stage | Degree of differentiation* | Survival (months) | Disease status | Intensity of staining | Area of staining (%) | Score |
|---|---|---|---|---|---|---|---|---|---|---|
| 53 | F | Right | Adenocarcinoma | IV | 3 | 117 | Alive without disease | 0 | 0 | 0 |
| 63 | M | Right | Adenocarcinoma | IV | 2 | 15 | Dead of disease | 3 | 20 | 4 |
| 68 | M | Right | Adenocarcinoma | III | 2 | 63 | Alive without disease | 0 | 0 | 0 |
| 74 | M | Right | Adenocarcinoma | III | 3 | 12 | Dead of disease | 3 | 80 | 6 |
| 61 | M | Left | Adenocarcinoma | III | 2 | 90 | Alive without disease | 2 | 50 | 4 |
| 72 | M | Rectum | Adenocarcinoma | III | 3 | 37 | Dead of disease | 2 | 75 | 5 |
| 43 | F | Left | Adenocarcinoma | IV | 3 | 0 | Postoperative death | 0 | 0 | 0 |
| 64 | M | Left | Adenocarcinoma | III | 2 | 72 | Alive without disease | 0 | 0 | 0 |
| 68 | M | Right | Mucinous adenocarcinoma | II | 2 | 48 | Alive without disease | 3 | 40 | 5 |
| 73 | F | Right | Adenocarcinoma | III | 3 | 110 | Alive without disease | 1 | 10 | 2 |
| 73 | F | Left | Adenocarcinoma | I | 2 | 72 | Alive without disease | 0 | 0 | 0 |
| 57 | M | Right | Adenocarcinoma | III | 2 | 94 | Dead without disease | 2 | 40 | 4 |
| 63 | M | Rectum | Adenocarcinoma | III | 3 | 15 | Dead of disease | 3 | 50 | 5 |
| 70 | F | Right | Mucinous adenocarcinoma | II | 2 | 38 | Alive without disease | 3 | 70 | 6 |
| 40 | F | Right | Adenocarcinoma | III | 2 | 16 | Dead of disease | 3 | 100 | 6 |
| 67 | M | Right | Adenocarcinoma | II | 2 | 46 | Alive without disease | 1 | 30 | 3 |
| 78 | M | Left | Mucinous adenocarcinoma | III | 1 | 70 | Dead of disease | 2 | 5 | 3 |
| 50 | M | Left | Adenocarcinoma | II | 2 | 48 | Alive without disease | 3 | 80 | 6 |
| 80 | M | Right | Adenocarcinoma | IV | 2 | 13 | Dead of disease | 3 | 50 | 5 |
| 63 | F | Left | Adenocarcinoma | III | 2 | 9 | Dead of disease | 3 | 80 | 6 |
| 76 | F | Right | Adenocarcinoma | III | 2 | 4 | Dead of disease | 3 | 80 | 6 |
| 60 | F | Left | Adenocarcinoma | II | 2 | 60 | Alive without disease | 1 | 50 | 3 |
| 50 | M | Rectum | Adenocarcinoma | I | 2 | 63 | Alive without disease | 0 | 0 | 0 |
| 36 | M | Rectum | Signet ring adenocarcinoma | III | 3 | 2 | Lost to follow-up | 0 | 0 | 0 |
| 30 | M | Rectum | Signet ring adenocarcinoma | III | 3 | 11 | Dead of disease | 0 | 0 | 0 |
| 77 | F | Right | Adenocarcinoma | III | 2 | 72 | Alive without disease | 0 | 0 | 0 |
| 53 | F | Left | Adenocarcinoma | IV | 2 | 6 | Dead of disease | 3 | 100 | 6 |
| 81 | M | Left | Adenocarcinoma | III | 3 | 2 | Lost to follow-up | 3 | 90 | 6 |
| 63 | M | Right | Adenocarcinoma | II | 2 | 43 | Alive without disease | 3 | 10 | 4 |
| 98 | F | Left | Signet ring adenocarcinoma | II | 3 | 0 | Postoperative death | 1 | 50 | 3 |
| 74 | M | Rectum | Adenocarcinoma | I | 2 | 52 | Alive without disease | 2 | 50 | 4 |
| 78 | F | Right | Adenocarcinoma | I | 2 | 55 | Alive without disease | 3 | 60 | 5 |
| 92 | F | Left | Adenocarcinoma | II | 2 | 58 | Dead without disease | 2 | 80 | 6 |
| 66 | F | Right | Adenocarcinoma | III | 2 | 46 | Alive without disease | 3 | 90 | 6 |
| 90 | F | Right | Mucinous adenocarcinoma | III | 3 | 0 | Postoperative death | 3 | 90 | 6 |
| 52 | M | Left | Adenocarcinoma | I | 2 | 46 | Alive without disease | 1 | 5 | 2 |
| 75 | M | Left | Adenocarcinoma | IV | 3 | 26 | Dead of disease | 2 | 20 | 4 |
| 81 | M | Left | Mucinous adenocarcinoma | III | 3 | 25 | Dead of disease | 3 | 100 | 6 |
| 34 | F | Right | Adenocarcinoma | I | 2 | 78 | Alive without disease | 0 | 0 | 0 |
| 81 | M | Left | Adenocarcinoma | III | 3 | 25 | Dead of disease | 1 | 10 | 2 |
Note:
*
1 = well differentiated; 2 = moderately differentiated; 3 = poorly differentiated.
Abbreviations: DCLK1, doublecortin and CaM kinase-like-1; AJCC, American Joint Committee on Cancer; M, male; F, female.