Table 2.
Incidence of overt hypothyroidism in elderly people
| Reference | Place | Sample | Age of participants | Measurementsa | Incidence (%) |
|---|---|---|---|---|---|
| Vanderpump et al2,b cohort study | United Kingdom | 1877, population based | ≥38 years | TSH (not informed), FT4 (not informed) | Overt Men: 0.6/1000 survivors/year Women: 3.5/1000 survivors/year |
| Gopinath et al25 cohort study | Australia | 951, population based | ≥55 years | TSH (>4.0 mIU/L), FT4 (<11.5 pmol/L) | Overt Men: 1.4%/5 year Women: 3.5%/5 year Subclinical Men: 0.7%/5 year Women: 2.5%/5 year |
Notes:
a
Measurements (cut-off for diagnosis of overt hypothyroidism);
b
as there are few studies evaluating incidence of overt hypothyroidism in elderly people, this study was included; mean age was 58 years (range 38–93 years).
Abbreviations: TSH, thyrotropin or thyroid stimulating hormone; FT4, free-thyroxine.