TABLE 1.

Clinical characteristics of lean and overweight/obese human subjects recruited in this study

Values are means ± S.E.

	Lean subjects (n = 25)	Overweight/obese subjects (n = 14)	p value
Age	42.5 ± 7.3 years	44.9 ± 5.6 years	0.089
BMIa	21.7 ± 2.1 kg/m2	28.6 ± 3.3 kg/m2	<0.001
Fasting glucoseb	4.7 ± 0.4 mm	4.8 ± 0.5 mm	0.363
2-h glucosec	5.8 ± 0.9 mm	7.5 ± 1.0 mm	<0.01
Fasting insulinb	3.8 ± 0.6 mIU/liter	5.7 ± 0.9 mIU/liter	0.016
HOMA-IRd	1.2 ± 0.2	1.8 ± 0.3	<0.01

^a BMI is BMI cutoff from lean and overweight/obese is 25.

^b Fasting glucose/insulin is glucose or insulin levels after an overnight 16-h fast.

^c 2-h glucose is glucose levels at the end of OGTT, i.e. the 2-h time point.

^d HOMA-IR = (fasting glucose (mm) × fasting insulin (mIU/liter))/22.5.