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Loss of maternal MeCP2_e2 results in failure to silence peg-1 expression in trophoblast cells. CXCR4 is a trophoblast cell marker. Xwt/Y and Xe2−Xwt placenta have minimal peg-1 expression, whereas Xe2−/Y placenta show elevated peg-1 levels in trophoblast cells (arrows). Scale bars, 50 μm.
