Putative regulatory sites for ascorbate biosynthesis and ascorbate recycling in C. reinhardtii. Enzymes depicted in red indicate the proteins whose mRNA levels are increased in response to oxidative stress (1 mm H2O2 and 0.1 mm tBuOOH) and those in magenta that show changes in mRNA levels only in response to H2O2 treatment. APX1 (ascorbate peroxidase), MSD3 (Mn superoxide dismutase), MDAR1 (monodehydroascorbate reductase), DHAR1 (dehydroascorbate reductase), GSH1 (γ-glutamylcysteine synthetase), GSH2 (glutathione synthetase), GSHR1/2 (glutathione reductase), GLDH (l-galactono-1,4-lactone dehydrogenase), VTC2 (GDP-l-galactose phosphorylase), ASC (ascorbate), MDA (monodehydroascorbate), and DHA (dehydroascorbate) are indicated.