FIGURE 1.
A and B, MTT cell proliferation assay with Casp2WT, Casp2KO, Casp2C320A, and Casp2S139A MEFs immortalized with SV40 (A) and with SV40/K-Ras (B). C and D, trypan blue assay of SV40-immortalized cells (C) and SV40/Ras-transformed cells (D). The data are presented as the means ± S.E. of results from experiments performed in triplicate. *p denotes the significant difference compared with wild-type cells.