FIGURE 2.
A, clonogenic assay with SV40-immortalized Casp2WT, Casp2KO, Casp2C320A, and Casp2S139A MEFs with colonies counted 7 days after seeding with data presented as the means ± S.E. from three independent experiments with each performed in triplicate. B, quantification of colonies formed in soft agar (in triplicate) by SV40/Ras-transformed Casp2WT, Casp2KO, Casp2C320A, and Casp2S139A cells on day 21. *p denotes significant difference. C, representative images of colonies on soft agar.