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. 2012 Feb 29;287(18):14782–14791. doi: 10.1074/jbc.M111.319616

FIGURE 4.

FIGURE 4.

Rab 4, Rab 11, and myosin Vb mediate recycling of MORs. A, 1-min kymographs depicting recycling events in control SEP-MOR cells (top) and cells co-expressing SEP-MOR and Rab 4 (S22N) (bottom). B, statistical analysis showing the number of recycling events 10 min after agonist exposure for both groups (n = 10 cells; error bars, S.E.). C, kymograph of control cells expressing SEP-MOR (top) or SEP-MOR and Rab11 (S29N) (bottom). D, average number of recycling events in cells transfected with SEP-MOR or in cells co-transfected with the dominant negative Rab11 (S29N) (n = 10 cells; bar, S.E.). E, 1-min kymographs showing recycling events in cells expressing SEP-MOR (top) or SEP-MOR and myoVb-tail (bottom). F, average number of recycling events 10 min after agonist exposure was plotted for both groups (n = 10 cells; error bar, S.E.).